How about this? This is the condition Elephant Man had.
Proteus syndrome is a
congenital disorder that causes
skin overgrowth and atypical
bone development, often accompanied by
tumors over half the body. Since Dr.
Michael Cohen identified it in
1979,
[1] only a few more than 200 cases have been confirmed worldwide, with estimates that about 120 people are currently alive with the condition.
[2] There may be many more than this, but those individuals correctly diagnosed usually have the most obvious manifestations of Proteus syndrome, leaving them severely disfigured. Proteus syndrome is named after the Greek sea-god
Proteus, who could change his shape.
This extremely rare condition would have remained obscure, were it not for the fact that
Joseph Merrick — immortalized as the "Elephant Man" for a look imparted by his large facial tumours and the grayish hue of his overgrown skin — was lately diagnosed as having a particularly severe case of Proteus syndrome rather than, or in addition to, the
neurofibromatosis that doctors once thought he had.
[3] Oddly, Merrick's left arm and his genitals were entirely unaffected by the condition that grotesquely deformed every other portion of his body.
Proteus syndrome causes an overgrowth of skin, bones, muscles, fatty tissues, and blood and lymphatic vessels.
Proteus syndrome is a progressive condition, wherein children are usually born without any obvious deformities. As they age, tumours as well as skin and bone growths appear. The severity and locations of these various
asymmetrical growths vary greatly but typically the skull, one or more limbs and soles of the feet will be affected. There is a risk of premature death in affected individuals due to
deep vein thrombosis and
pulmonary embolism caused by the vessel malformations that are associated with this disorder. Further risks may occur due to the mass of extra tissue - Merrick himself died when the weight of his head dislocated his neck whilst asleep.
The disorder itself does not directly cause learning impairments: the distribution of intelligence among sufferers of Proteus syndrome mirrors that of the general population. However, the growths may cause secondary damage to the nervous system leading to cognitive disability. In addition, the presence of visible deformity may have a negative effect on the social experiences of the sufferer, causing cognitive and social deficits.
Proteus syndrome - Wikipedia, the free encyclopedia
There is a number of other bone disfigurement type of illnesses but I'd think that if anyone had such a thing, they would look far worse than these Bogdanoff brothers and the disfigurement wouldn't be contained on the face only, it would manifest in other parts of the body?
They just look like a bad case of PS, kinda like what that Wilderstein/Cat lady did to her face.